APRAIZE 20MG TABLET 4S

Product Introduction:

Apraize 20mg Tablet contains Apremilast, a phosphodiesterase 4 (PDE4) inhibitor used to treat certain inflammatory conditions, notably psoriasis and psoriatic arthritis. By inhibiting the enzyme PDE4, Apremilast helps reduce the production of inflammatory mediators in the body, thereby alleviating symptoms associated with these conditions.

Apraize 20mg Tablet can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. You may need to monitor your weight regularly while taking the medicine as it may cause weight loss.

Using this medicine may cause few common side effects such as nausea, diarrhea, vomiting, headache, and upper respiratory tract infection. If these side effects persist or get worse, let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know all the other medicines you are taking. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.

Benefits:

1. Treatment of Psoriasis: Apraize 20mg Tablet effectively reduces the symptoms of psoriasis, including redness, itching, and scaling of the skin.
2. Management of Psoriatic Arthritis: It helps alleviate joint pain, swelling, and stiffness associated with psoriatic arthritis, improving mobility and quality of life for patients.
3. Oral Administration: Unlike some other treatments for psoriasis and psoriatic arthritis, which may require injections or infusions, Apraize 20mg Tablet is taken orally, offering convenience for patients.

Side Effects:

Common side effects of Apraize 20mg Tablet may include:

• Nausea
• Diarrhea
• Headache
• Upper respiratory tract infections
• Weight loss

Less common but more serious side effects may include:

• Depression or mood changes
• Suicidal thoughts or behavior
• Severe diarrhea
• Allergic reactions

Usage Guidelines:

• Dosage: The usual adult dosage is one tablet (20mg) taken orally twice daily, preferably with food.
• Duration: Follow your doctor’s instructions regarding the duration of treatment. Do not discontinue the medication abruptly without consulting your doctor, as this may lead to worsening of symptoms.
• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Overdose: In case of overdose, seek medical attention immediately. Overdose symptoms may include nausea, vomiting, diarrhea, and headache.

Drug Interactions:

• CYP450 Inducers/Inhibitors: Apremilast is primarily metabolized by the CYP450 enzyme system. Co-administration with strong CYP450 inducers (e.g., rifampin, carbamazepine) or inhibitors (e.g., ketoconazole, erythromycin) may alter its metabolism and efficacy. Dosage adjustments may be necessary.
• Immunosuppressants: Concurrent use with other immunosuppressant medications may increase the risk of immunosuppression and susceptibility to infections.
• Antidepressants: Use caution when combining Apraize 20mg Tablet with antidepressant medications, as it may increase the risk of mood changes or depression.

Always inform your healthcare provider about all medications you are taking, including prescription, over-the-counter, and herbal products, to avoid potential drug interactions or adverse effects. Follow your doctor’s recommendations for the safest and most effective use of Apraize 20mg Tablet.

SAFETY ADVICE

Alcohol

CAUTION

Caution is advised when consuming alcohol with Apraize 20mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Apraize 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Apraize 20mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Apraize 20mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Apraize 20mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Apraize 20mg Tablet may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Apraize 20mg Tablet is safe to use in patients with liver disease. No dose adjustment of Apraize 20mg Tablet is recommended.