APIGY 2.5MG TABLET 10S

Product Introduction:

Apigy 2.5mg Tablet is a medication belonging to the class of direct oral anticoagulants (DOACs), specifically a factor Xa inhibitor. It is used for various medical conditions where there is a risk of blood clot formation, such as preventing stroke in patients with nonvalvular atrial fibrillation, treating deep vein thrombosis (DVT), and preventing pulmonary embolism (PE) after hip or knee replacement surgery.

Apigy 2.5mg Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone elective knee or hip replacement surgeries. It can be taken with or without food and it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases.

Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.

The most common side effect of Apigy 2.5mg Tablet is bleeding more easily than normal, for example, having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include hematoma, anemia, and nausea.

Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding, or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Benefits:

1. Blood Clot Prevention: Apigy reduces the risk of blood clot formation by inhibiting the activity of factor Xa, an enzyme involved in the blood clotting process.
2. Stroke Prevention: It is effective in reducing the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, a common heart rhythm disorder.
3. Treatment of Deep Vein Thrombosis and Pulmonary Embolism: Apigy is used to treat and prevent recurrence of deep vein thrombosis (DVT) and pulmonary embolism (PE), potentially life-threatening conditions.

Side Effects:

1. Bleeding: The most common side effect of Apigy is bleeding, which can range from minor to severe. This includes nosebleeds, bruising, gastrointestinal bleeding, and in rare cases, bleeding in the brain.
2. Allergic Reactions: Some individuals may experience allergic reactions to Apigy, which can manifest as rash, itching, swelling, or difficulty breathing. Seek medical attention if any allergic reactions occur.

Usage Guidelines:

1. Dosage: The dosage of Apigy is determined by the prescribing healthcare provider based on the patient’s medical condition, kidney function, and other factors.
2. Administration: Apigy tablets are taken orally with or without food, as directed by the healthcare provider.
3. Duration of Use: Follow the prescribed duration of treatment with Apigy. Do not stop taking the medication abruptly without consulting your doctor, as it may increase the risk of blood clots.
4. Missed Dose: If a dose is missed, take it as soon as remembered on the same day. If it is close to the time for the next dose, skip the missed dose and continue with the regular dosing schedule.

Drug Interactions:

1. Other Anticoagulants and Antiplatelet Drugs: Concurrent use with other blood-thinning medications may increase the risk of bleeding.
2. Certain Medications: Drugs that affect liver enzymes or kidney function may interact with Apigy, so inform your doctor about all medications being taken, including over-the-counter drugs and herbal supplements.
3. Herbal Supplements: Certain herbal supplements like ginkgo biloba or garlic may increase the risk of bleeding when taken with Apigy.

Precautions:

1. Bleeding Risk: Patients taking Apigy should be monitored for signs of bleeding and advised to avoid activities that may increase the risk of injury.
2. Kidney Function: Inform your doctor if you have kidney problems, as dosage adjustments may be necessary.
3. Pregnancy and Breastfeeding: Use of Apigy should be avoided during pregnancy unless the benefits outweigh the risks. It is not recommended during breastfeeding.

Always consult your healthcare provider for personalized advice regarding the use of Apigy 2.5mg Tablet and any adjustments to your treatment plan.

SAFETY ADVICE

Alcohol

CAUTION

Caution is advised when consuming alcohol with Apigy 2.5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Apigy 2.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Apigy 2.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Apigy 2.5mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Apigy 2.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Apigy 2.5 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Apigy 2.5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Apigy 2.5mg Tablet may be needed. Please consult your doctor.
However, Apigy 2.5mg Tablet dose adjustment may not be needed in patients with the mild liver disease.