AMTAS-AT TABLET 15S

Product Introduction:

Amtas-AT Tablet is a combination medication containing Amlodipine (5mg) and Atenolol (50mg). Amlodipine is a calcium channel blocker, while Atenolol is a beta-blocker. This combination is commonly prescribed to treat high blood pressure (hypertension) and chest pain (angina) associated with coronary artery disease.

Amtas-AT Tablet may be taken with or without food. Take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

It may cause side effects like headache, slow heart rate, and nausea. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.

Benefits:

1. Blood Pressure Control: Amlodipine relaxes blood vessels, allowing for smoother blood flow and lowering blood pressure levels. Atenolol reduces heart rate and workload on the heart, further lowering blood pressure.
2. Angina Relief: Amlodipine dilates coronary arteries, increasing blood flow to the heart muscle, while Atenolol reduces the heart’s oxygen demand, providing relief from angina symptoms.
3. Complementary Action: The combination of Amlodipine and Atenolol offers synergistic effects in controlling blood pressure and managing angina.

Side Effects:

While Amtas-AT Tablet is generally well-tolerated, some individuals may experience side effects, including:

• Dizziness or lightheadedness
• Fatigue
• Headache
• Nausea
• Peripheral edema (swelling of the ankles, feet, or hands)
• Bradycardia (slow heart rate) with Atenolol
• Cold extremities (due to decreased blood flow) with Atenolol

Rare but serious side effects may include:

• Irregular heartbeat
• Chest pain
• Fainting
• Difficulty breathing

If any severe or persistent side effects occur, seek medical attention promptly.

Usage Guidelines:

1. Dosage: Take Amtas-AT Tablet exactly as prescribed by your healthcare provider.
2. Administration: Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
3. Timing: Take the tablet at the same time each day to maintain consistent blood levels of the medication.
4. Food Interactions: Amtas-AT Tablet can be taken with or without food.
5. Duration of Use: Continue taking the medication for the prescribed duration, even if you feel well. Do not stop taking it abruptly without consulting your healthcare provider.

Drug Interactions:

• Amtas-AT Tablet may interact with other medications, including:
  • Other blood pressure-lowering medications
  • Certain antibiotics (e.g., clarithromycin)
  • Antifungal medications (e.g., itraconazole)
  • HIV protease inhibitors
  • St. John’s wort
• Inform your healthcare provider about all medications, supplements, and herbal products you are currently taking to avoid potential interactions.

Precautions:

1. Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before taking Amtas-AT Tablet. It should be used during pregnancy only if clearly needed.
2. Heart Conditions: Use caution when taking Amtas-AT Tablet if you have certain heart conditions such as heart block, bradycardia, or heart failure.
3. Diabetes: Beta-blockers like Atenolol can mask some of the symptoms of low blood sugar in diabetes. Monitor your blood sugar levels closely if you have diabetes.
4. Elderly Patients: Dosage adjustments may be necessary for elderly patients, as they may be more sensitive to the effects of beta-blockers and calcium channel blockers.

Always follow the advice of your healthcare provider regarding the use of Amtas-AT Tablet, and do not exceed the recommended dosage or duration of treatment without consulting them first.

SAFETY ADVICE

Alcohol

UNSAFE

It is unsafe to consume alcohol with Amtas-AT Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Amtas-AT Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Amtas-AT Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Amtas-AT Tablet may cause side effects which could affect your ability to drive.
Amtas-AT Tablet may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.

Kidney

CAUTION

Amtas-AT Tablet should be used with caution in patients with kidney disease. Dose adjustment of Amtas-AT Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is recommended and can help in better dose adjustment.

Liver

CAUTION

Amtas-AT Tablet should be used with caution in patients with liver disease. Dose adjustment of Amtas-AT Tablet may be needed. Please consult your doctor.
Amtas-AT Tablet is started at a lower dose in patients with liver disease and further increased slowly with careful monitoring.