AMLOSAFE MT 25MG TABLET 10S

Product Introduction:

AmloSafe MT 25mg Tablet is a combination medication composed of two active ingredients: Amlodipine (5mg) and Metoprolol Succinate (25mg). Amlodipine belongs to the class of calcium channel blockers, while Metoprolol Succinate is a beta-blocker. This combination is commonly prescribed for the treatment of hypertension (high blood pressure) and certain cardiovascular conditions where both vasodilation and heart rate reduction are desired.

You can take AmloSafe MT 25mg Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

It may cause side effects like headache, ankle swelling, skin rash, slow heart rate, nausea,a nd depression. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.

Benefits:

1. Blood Pressure Management: Amlodipine and Metoprolol Succinate work synergistically to lower blood pressure through different mechanisms, effectively reducing the risk of cardiovascular complications associated with hypertension.
2. Cardiovascular Protection: Both medications offer protective effects on the cardiovascular system, potentially reducing the risk of heart failure, stroke, and other cardiovascular events.
3. Heart Rate Control: Metoprolol Succinate helps regulate heart rate, which can be beneficial in conditions such as angina and certain types of arrhythmias.

Side Effects:

Common side effects of AmloSafe MT 25mg Tablet may include:

• Dizziness
• Fatigue
• Headache
• Swelling of ankles or feet
• Flushing
• Nausea
• Constipation or diarrhea
• Bradycardia (slow heart rate)
• Hypotension (low blood pressure)

Rare but serious side effects may include:

• Allergic reactions
• Exacerbation of heart failure symptoms
• Bronchospasm (especially in patients with a history of asthma)
• Masking of symptoms of low blood sugar in diabetic patients

If any adverse reactions occur, patients should seek medical attention promptly.

Usage Guidelines:

• The usual recommended dose of AmloSafe MT 25mg Tablet is one tablet taken orally once daily.
• It can be taken with or without food, but should be taken consistently at the same time each day.
• Patients should follow their healthcare provider’s instructions regarding dosage and duration of treatment.
• Abrupt discontinuation of beta-blockers like Metoprolol Succinate should be avoided, as it may lead to rebound hypertension or worsening of angina symptoms.

Drug Interactions:

Certain medications may interact with Amlodipine and Metoprolol Succinate, potentially affecting their efficacy or increasing the risk of adverse effects. Notable drug interactions include:

• Other antihypertensive medications: Concurrent use may lead to additive hypotensive effects.
• Calcium channel blockers: Increased risk of bradycardia or heart block.
• Beta-blockers: Increased risk of bradycardia, hypotension, and heart block.
• Drugs that inhibit or induce CYP3A4 enzymes: May affect the metabolism of Amlodipine, leading to altered blood levels and efficacy.

Patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking to avoid potential drug interactions.

It’s crucial for patients to adhere to their prescribed dosage regimen, monitor for any side effects, and attend regular follow-up appointments with their healthcare provider for blood pressure monitoring and medication adjustments as needed.

SAFETY ADVICE

Alcohol

UNSAFE

It is unsafe to consume alcohol with AmloSafe MT 25mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

AmloSafe MT 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

AmloSafe MT 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

AmloSafe MT 25mg Tablet may cause side effects which could affect your ability to drive.
AmloSafe MT 25mg Tablet may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.

Kidney

SAFE IF PRESCRIBED

AmloSafe MT 25mg Tablet is safe to use in patients with kidney disease. No dose adjustment of AmloSafe MT 25mg Tablet is recommended.

Liver

CAUTION

AmloSafe MT 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of AmloSafe MT 25mg Tablet may be needed. Please consult your doctor.