AMLOSAFE-LS 5/5MG TABLET 10S

Product Introduction:

AmloSafe-LS 5/5mg Tablet is a pharmaceutical formulation containing two active ingredients: Amlodipine (5mg) and Lisinopril (5mg). Amlodipine is classified as a calcium channel blocker, while Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor. This combination medication is commonly prescribed for the management of hypertension (high blood pressure) in patients who require multiple drugs to achieve optimal blood pressure control.

You can take Amlosafe-LS 5/5mg Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.

It may cause side effects like ankle swelling, headache, cough, weakness, and tiredness. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.

Benefits:

1. Blood Pressure Control: Amlodipine and Lisinopril work synergistically to lower blood pressure, reducing the risk of cardiovascular complications such as stroke, heart attack, and kidney damage.
2. Cardiovascular Protection: Both medications offer protective effects on the cardiovascular system, potentially reducing the risk of heart failure and other cardiovascular events.
3. Simplified Regimen: Combining two antihypertensive agents into a single tablet enhances convenience and improves patient adherence to treatment regimens.

Side Effects:

Common side effects of AmloSafe-LS 5/5mg Tablet may include:

• Dizziness
• Headache
• Fatigue
• Cough (associated with Lisinopril)
• Peripheral edema (swelling of ankles or feet)
• Flushing
• Nausea

Rare but serious side effects may include:

• Hypotension (low blood pressure)
• Hyperkalemia (high potassium levels)
• Allergic reactions

If any adverse reactions occur, patients should seek medical attention promptly.

Usage Guidelines:

• The typical recommended dosage of AmloSafe-LS 5/5mg Tablet is one tablet taken orally once daily.
• It can be administered with or without food, but consistency in administration time is important.
• Patients should adhere to the dosage regimen prescribed by their healthcare provider and avoid sudden discontinuation of the medication without consulting a physician, as abrupt cessation may lead to rebound hypertension.

Drug Interactions:

Certain medications may interact with Amlodipine and Lisinopril, potentially altering their effectiveness or increasing the risk of adverse effects. Notable drug interactions include:

• Potassium supplements or potassium-sparing diuretics: Concurrent use may increase the risk of hyperkalemia.
• Nonsteroidal anti-inflammatory drugs (NSAIDs): These drugs may attenuate the antihypertensive effects of Amlodipine and increase the risk of renal impairment.
• Other antihypertensive agents: Concurrent use may result in additive hypotensive effects.
• Certain antibiotics, antifungal agents, and antidepressants may interact with Lisinopril, necessitating dose adjustments or close monitoring.

Patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking to avoid potential drug interactions.

It’s crucial for patients to adhere to their prescribed dosage regimen, monitor for any side effects, and attend regular follow-up appointments with their healthcare provider for blood pressure monitoring and medication adjustments as needed.

SAFETY ADVICE

Alcohol

UNSAFE

It is unsafe to consume alcohol with Amlosafe-LS 5/5mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Amlosafe-LS 5/5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Amlosafe-LS 5/5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Amlosafe-LS 5/5mg Tablet may cause side effects which could affect your ability to drive.
Amlosafe-LS 5/5mg Tablet may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.

Kidney

CAUTION

Amlosafe-LS 5/5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Amlosafe-LS 5/5mg Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is recommended for better dose adjustment.

Liver

CAUTION

Amlosafe-LS 5/5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amlosafe-LS 5/5mg Tablet may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.