Product Introduction:
Amaryl MP 2mg Tablet is a medication combining three active ingredients: Glimepiride (2mg), Metformin (500mg), and Pioglitazone (15mg). Glimepiride belongs to the sulfonylurea class, Metformin is a biguanide, and Pioglitazone is a thiazolidinedione. This combination is used for the management of type 2 diabetes mellitus by targeting multiple pathways involved in glucose regulation.
Amaryl MP 2mg Tablet should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).
Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, diarrhea, stomach pain, headache, bone fracture, and respiratory tract infection.
Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.
Benefits:
- Blood Sugar Control: Amaryl MP 2mg Tablet helps regulate blood sugar levels effectively through various mechanisms. Glimepiride stimulates insulin release, Metformin reduces hepatic glucose production, and Pioglitazone improves insulin sensitivity in peripheral tissues.
- Weight Management: Metformin and Pioglitazone components of Amaryl MP may aid in weight management. While Metformin generally does not cause weight gain and may even promote weight loss, Pioglitazone may cause slight weight gain but is associated with improvements in body composition.
- Improved Insulin Sensitivity: Pioglitazone enhances insulin sensitivity in muscle and adipose tissue, which can lead to improved glycemic control.
Side Effects:
Common side effects of Amaryl MP 2mg Tablet may include:
- Hypoglycemia (low blood sugar)
- Nausea or vomiting
- Diarrhea
- Abdominal discomfort
- Weight gain (more common with Pioglitazone)
- Headache
- Dizziness
Rare but serious side effects may include:
- Lactic acidosis (rare but potentially fatal)
- Heart failure (especially with Pioglitazone)
- Bone fractures (more common with long-term use of Pioglitazone)
- Liver problems
Usage Guidelines:
- Amaryl MP 2mg Tablet should be taken exactly as prescribed by the healthcare provider.
- The usual starting dose is one tablet once daily with breakfast or the first main meal of the day.
- Dosage adjustments may be necessary based on blood sugar levels and individual response to the medication.
- Regular monitoring of blood sugar levels is essential as directed by the healthcare provider.
- Amaryl MP 2mg Tablet should be swallowed whole with a glass of water and not crushed or chewed.
Drug Interactions:
- Amaryl MP 2mg Tablet may interact with various medications, including:
- Other oral diabetes medications
- Insulin
- Certain antibiotics (e.g., sulfa drugs)
- Certain heart medications (e.g., beta-blockers)
- Certain antifungal medications
- Inform the healthcare provider about all medications, supplements, and herbal products being taken to avoid potential interactions.
Important Note:
Consult a healthcare professional or pharmacist for personalized advice regarding the use of Amaryl MP 2mg Tablet, including dosing, potential side effects, and drug interactions. This information serves as a general guideline and should not replace professional medical advice.
SAFETY ADVICE
Alcohol
Pregnancy
Breast feeding
Driving
Kidney
Use of Amaryl MP 2mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
Use of Amaryl MP 2mg Tablet is not recommended in patients with severe liver disease.