AMICON PLUS TABLET 10S

Product Introduction:

AMICON PLUS Tablet is a combination medication that includes two active ingredients: Amitriptyline (12.5mg) and Chlordiazepoxide (5mg). Amitriptyline is a tricyclic antidepressant (TCA), while Chlordiazepoxide is a benzodiazepine. This combination is primarily prescribed for the treatment of depressive disorders accompanied by anxiety or tension.

AMICON PLUS Tablet is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions.

Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Benefits:

1. Treatment of Depressive Disorders: AMICON PLUS Tablet helps alleviate symptoms associated with depression, such as persistent sadness, loss of interest in activities, changes in appetite or sleep, and feelings of worthlessness or guilt.
2. Anxiolytic Effect: Chlordiazepoxide provides anxiolytic (anti-anxiety) effects, helping to reduce feelings of tension and anxiety that often accompany depressive symptoms.
3. Combination Therapy: By combining Amitriptyline and Chlordiazepoxide, AMICON PLUS Tablet offers synergistic effects, providing comprehensive relief for patients experiencing both depressive symptoms and anxiety or tension.
4. Convenience: The combination of two medications in a single tablet enhances convenience and compliance for patients who require treatment for both depression and anxiety.

Side Effects:

Common side effects of AMICON PLUS Tablet may include:

• Drowsiness or sedation
• Dry mouth
• Blurred vision
• Dizziness or lightheadedness
• Constipation
• Urinary retention
• Weight gain
• Increased appetite
• Sexual dysfunction

Serious side effects are rare but may include:

• Suicidal thoughts or behavior (especially in young adults)
• Respiratory depression (especially when taken with other central nervous system depressants)
• Hypotension (low blood pressure)
• Paradoxical reactions (unusual reactions opposite to the expected effects)

Usage Guidelines:

• Take AMICON PLUS Tablet exactly as prescribed by your healthcare provider.
• The dosage may vary depending on the severity of symptoms and individual patient factors.
• It is usually taken orally, with or without food, one to three times daily.
• Do not suddenly stop taking AMICON PLUS Tablet without consulting your doctor, as abrupt discontinuation may lead to withdrawal symptoms.
• Avoid alcohol and other central nervous system depressants while taking this medication, as they may increase the risk of side effects such as drowsiness and respiratory depression.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Drug Interactions:

• AMICON PLUS Tablet may interact with other medications, including:
  • Other antidepressants or antipsychotics, increasing the risk of serotonin syndrome.
  • Central nervous system depressants, including alcohol, benzodiazepines, opioids, and muscle relaxants, leading to additive sedative effects.
  • Monoamine oxidase inhibitors (MAOIs), increasing the risk of hypertensive crisis.
• Inform your doctor about all medications, supplements, and herbal products you are currently taking before starting AMICON PLUS Tablet to prevent potential drug interactions.

Always consult your healthcare provider for personalized advice regarding the use of AMICON PLUS Tablet, especially regarding dosages, side effects, and potential interactions.

SAFETY ADVICE

Alcohol

UNSAFE

It is unsafe to consume alcohol with AMICON PLUS Tablet.

Pregnancy

CONSULT YOUR DOCTOR

AMICON PLUS Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

AMICON PLUS Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

AMICON PLUS Tablet may cause side effects which could affect your ability to drive.
As AMICON PLUS Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

AMICON PLUS Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of AMICON PLUS Tablet may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

AMICON PLUS Tablet should be used with caution in patients with liver disease. Dose adjustment of AMICON PLUS Tablet may be needed. Please consult your doctor.