AMICIN 500MG INJECTION 2ML

Product Introduction:

AMICIN 500mg Injection contains Amikacin as the active ingredient, belonging to the aminoglycoside class of antibiotics. It is primarily used to treat serious bacterial infections caused by susceptible strains of bacteria. Amikacin works by inhibiting bacterial protein synthesis, ultimately leading to bacterial cell death.

Amicin 500mg Injection works by stopping the growth of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional and should not be self-administered. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.

Common side effects of this medicine include injection site reactions and increased blood urea. Consult your doctor if any of these side effects persist or if your condition does not improve despite treatment.

Some patients receiving high doses may develop balance disorder (loss of balance), kidney damage, and hearing loss. Therefore, please follow all the instructions given by your doctor while using this medicine. Your doctor may also monitor you with regular kidney function tests, hearing tests, and urine tests during treatment. This medication is not recommended for use during pregnancy. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Benefits:

1. Broad-Spectrum Antibacterial Activity: AMICIN 500mg Injection is effective against a wide range of bacterial infections, including Gram-negative and some Gram-positive bacteria.
2. Treatment of Serious Infections: Amikacin is particularly useful in treating severe or life-threatening infections such as sepsis, pneumonia, urinary tract infections, meningitis, and certain types of hospital-acquired infections.
3. Potency: Amikacin is known for its potency against certain bacteria that may be resistant to other antibiotics, making it a valuable option in the treatment of multidrug-resistant infections.
4. Parenteral Administration: Being available in injectable form, AMICIN 500mg Injection allows for rapid administration and ensures high blood levels of the antibiotic, especially in critically ill patients or those unable to take oral medications.

Side Effects:

Common side effects of AMICIN 500mg Injection may include:

• Nausea or vomiting
• Diarrhea
• Injection site reactions (pain, redness, swelling)
• Headache
• Dizziness or lightheadedness
• Kidney damage (with prolonged or high-dose therapy)

Serious side effects are rare but may include:

• Allergic reactions (rash, itching, swelling, difficulty breathing)
• Hearing loss or ringing in the ears (ototoxicity)
• Neuromuscular blockade (especially with high doses or prolonged use)
• Electrolyte disturbances

Usage Guidelines:

• AMICIN 500mg Injection should be administered under the supervision of a healthcare professional, usually in a hospital setting.
• The dosage and duration of treatment will depend on the type and severity of the infection, as well as the patient’s age, weight, and renal function.
• The injection is typically given intravenously or intramuscularly. It should not be injected into the buttock muscle (gluteal region) due to the risk of nerve damage.
• Before administering the injection, check for any signs of precipitation or discoloration in the solution, and ensure proper dilution if required.
• Follow aseptic techniques during administration to minimize the risk of contamination and infection.

Drug Interactions:

• AMICIN 500mg Injection may interact with other medications, including:
  • Other nephrotoxic or ototoxic drugs, such as certain antibiotics (e.g., vancomycin, gentamicin), diuretics (e.g., furosemide), or chemotherapy agents, increasing the risk of kidney or hearing problems.
  • Neuromuscular blocking agents, which may potentiate the neuromuscular blockade effect of Amikacin.
  • Certain medications that may affect kidney function or electrolyte balance, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or ACE inhibitors.

Always inform your healthcare provider about all medications, supplements, and herbal products you are currently taking before starting AMICIN 500mg Injection to prevent potential drug interactions.

This injection should only be used under the supervision of a qualified healthcare professional, and patients should follow their doctor’s instructions carefully.

SAFETY ADVICE

Alcohol

SAFE

Consuming alcohol with Amicin 500mg Injection does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Amicin 500mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Amicin 500mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Amicin 500mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Amicin 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Amicin 500mg Injection may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Amicin 500mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Amicin 500mg Injection may not be needed in these patients. Please consult your doctor.