AMBISTRYN S 1GM INJECTION 1 VIAL

Product Introduction:

Ambistryn S 1gm Injection is a medication containing Streptomycin, which belongs to the class of antibiotics known as aminoglycosides. It is used in the treatment of various bacterial infections by inhibiting bacterial protein synthesis. Streptomycin is particularly effective against Mycobacterium tuberculosis, the bacteria responsible for tuberculosis (TB), and is commonly used in combination therapy for this condition.

Ambistryn S 1gm Injection is given as an injection directly into a muscle under the supervision of a healthcare professional. It should be used regularly as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.

This medicine may cause a skin rash, vomiting, fever, and vertigo as side effects. Therefore, please follow all the instructions given by your doctor while using this medicine. Your doctor may monitor you with regular kidney function tests, hearing tests, and urine tests during treatment. Consult your doctor if your condition does not improve or if any of the side effects bother you.

Use caution while driving or doing anything that requires concentration as this medicine may cause dizziness. It is not recommended for use during pregnancy. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Benefits:

1. Treatment of Tuberculosis: Streptomycin is a first-line medication for the treatment of tuberculosis, particularly when resistance to other antibiotics is a concern.
2. Broad-Spectrum Antibacterial Activity: Streptomycin exhibits activity against a wide range of bacterial pathogens, making it useful in the treatment of various bacterial infections, including those affecting the respiratory system, urinary tract, and other organs.
3. Synergy in Combination Therapy: When used in combination with other antibiotics, Streptomycin can enhance the effectiveness of treatment and help prevent the development of antibiotic resistance.

Side Effects:

Common side effects of Ambistryn S 1gm Injection may include:

• Nausea
• Vomiting
• Diarrhea
• Dizziness
• Headache
• Injection site reactions (pain, redness, swelling)
• Nephrotoxicity (kidney damage)
• Ototoxicity (hearing loss or ringing in the ears)

Usage Guidelines:

• Ambistryn S 1gm Injection should be administered by a healthcare professional, usually via intramuscular injection.
• The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient’s age, weight, and kidney function.
• It is essential to complete the full course of treatment as prescribed by the healthcare provider, even if symptoms improve before the treatment is completed.
• Dosage adjustments may be necessary in patients with impaired kidney function to prevent the accumulation of Streptomycin and reduce the risk of nephrotoxicity.

Drug Interactions:

• Ambistryn S 1gm Injection may interact with other medications, including:
  • Other ototoxic or nephrotoxic drugs, such as certain antibiotics (e.g., vancomycin, amikacin) or chemotherapeutic agents (e.g., cisplatin)
  • Diuretics
  • Neuromuscular blocking agents
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Inform the healthcare provider about all medications, supplements, and herbal products being taken to avoid potential interactions.

Important Note:

Streptomycin therapy should be closely monitored by a healthcare professional, especially in patients with preexisting kidney impairment or those at risk of developing hearing loss. It is essential to weigh the potential benefits against the risks of treatment, considering the potential for side effects and interactions. This information serves as a general guideline and should not replace professional medical advice.

SAFETY ADVICE

Alcohol

SAFE

Consuming alcohol with Ambistryn S 1gm Injection does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Ambistryn S 1gm Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Ambistryn S 1gm Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Ambistryn S 1gm Injection may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Ambistryn S 1gm Injection should be used with caution in patients with kidney disease. Dose adjustment of Ambistryn S 1gm Injection may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Ambistryn S 1gm Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Ambistryn S 1gm Injection may not be needed in these patients. Please consult your doctor.